Die Untersuchung der Lungen von Patienten, die zu verschiedenen Zeitpunkten einer COVID-19-Pneumonie gestorben waren, zeigt, dass die Erkrankung in den Lungen in 2 Phasen abläuft.
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[...] The pioneering work of Barker et al. [5–7] on the association between low birth weight and increased risk of adult hypertension [5] and cardiovascular disease [6] led to the hypothesis that intrauterine and infantile growth failure due to undernutrition determines adult susceptibility to chronic diseases. [...] The first study was based on a cohort that included all European Jews born between 1920 and 1945 who immigrated to Israel before (‘non-exposed’) or after (‘exposed’) WWII. Based on data from the Israel National Cancer Registry, it was found that exposure (vs. non-exposure) was associated with a significant increase in incidence in all-site cancer in men (relative risks, RRs = 1.2–3.5 in different birth cohorts) and women (RRs = 1.3–2.3), with an age gradient such that the strongest associations were observed in the youngest birth cohort. Increased risk was also observed for breast (women), colorectal (both sexes), and lung (men) cancer, with an age gradient found for the f...
Atopic eczema in children: another harmful sequel of divorce Parents of participants of the ongoing LISA birth cohort study were asked to give information on life events, such as severe disease or death of a family member, unemployment, or divorce of the parents. Lifetime prevalence of atopic eczema and incidence after the assessment period for life events were compared. Results: Prevalence of AE until the age of 4 years was 21.4%. Reported life events within the first 2 years were: severe disease (17.5%) or death (8.4%) of a family member, divorce/separation (3.4%), and unemployment (2.7%). Divorce/separation was associated with a significantly [odds ratio (OR) 3.59, 95% confidence interval (CI) 1.69-7.66] increased and disease with a significantly (OR 0.29, 95% CI 0.13-0.68) decreased incidence of AE for the subsequent 2 years of life... Link
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